Removing it fixes Responsive Lightbox. Luckily, we aren’t really using it anymore. Might be worth trying to figure out why it conflicts though, or at least making a note of it in the docs somewhere.
This would be a great feature. There is a super easy workaround though: end the image URL with “#” as in “my-image.png#”. The plugin regex won’t pick it up, but browsers load it normally (tested in Chrome and Firefox, Safari).