I use “responsive lightbox” as is, and it works good on most platforms, but with the “resonsive” part I have my difficulties. When I test my gallery on iphones the thumbs are dispsplaying correctely but the large pics are only shown in a very small size. There must be a margin issue or something, but like this the responsiveness is is not usable.
The plugin provides 4, completely different, scripts – 2 of them being build with responsiveness in mind especially (SwipeBox and Nivo Lightbox). 2 other scripts are responsive too but are a bit older and may have not been tested for all, especially the latest, devices.