I tried Responsive Lightbox this evening and it seems like it works fine for my personal WP blog, but I noticed a weird bug when opening an image that is part of a Jetpack ‘carousel’ gallery.
Example: http://www.ocabj.net/recap-inside-basel-geneva-2013-by-watchtime-in-los-angeles/
At the bottom of the post in the above link, there is a tiled gallery. If you click on one of those tiled images to open the Jetpack carousel gallery, then close out the carousel (click X or use Escape key on keyboard), then after that click on one of the standalone images such as the one at the beginning of the post, the Responsive Lightbox opens, but the image does not display. If you reload the page, the standalone images will load via RL, but once you open the Jetpack carousel gallery, any attempts to open a standalone image fails to display in RL.